Understanding Immune Checkpoints in Immunology and Cancer
At Enzo, we offer a complete set of solutions for immuno-oncology research including antibodies, ELISA kits,
and recombinant proteins. Our diverse scientific and technical expertise has helped us create innovative assays
and reagents to help support immuno-oncology research. We provide flexible and validated tools to help you
generate reliable and consistent results.
TLRs play a role in the innate immune system, detecting pathogen-associated molecule patterns (PAMPs) of bacterial, viral, fungal, and protozoal origin.
Superior Performance from Carefully Engineered TNF Superfamily Ligands
MEGACD40L? Protein (soluble) (human), (recombinant)
B cell lymphocyte activation by various CD40L constructs. PBMCs were treated for 48 hrs in media containing serially diluted CD40L, CD40L + 2 μg/mL Enhancer, or MEGACD40L? Protein. Cells were dual-stained with α-human CD19–PE and α-human CD86–APC and analyzed by flow cytometry.
Data are presented as the percent of CD19+ B cells that co-stain as CD86+.
Death Receptor Ligands
Members of the tumor necrosis factor (TNF) receptor gene superfamily bind to extrinsic ligands and transduce intracellular signals leading to the destruction
of the cell. Ligands, such as FasL and TNF-α, hold potential as targets for therapeutic and diagnostic applications.
Features an N-Terminus linker shown to improve stability
Enhanced immune activation compared to other recombinant ligands
Mimics glycosylation of native human FasL
Induction of Cell Death with SUPERFASLIGAND? Protein
Jurkat cells were incubated with the indicated concentration of SuperFasL and cell proliferation was assayed. % Viability was determined in comparison to control wells with no SuperFasL.
Quantify Biomarkers Of Inflammation With ELISA Kits
High-Specificity ELISAs for Innate and Adaptive Immune Research
Enzo offers a large variety of immunoassay kits in both immunometric and competitive assay formats. As scientists and manufacturers of kits, we understand
the critical nature of your research. Each kit is put through rigorous testing to ensure high precision, accuracy, sensitivity, and specificity. You can be confident
that you will obtain reproducible results, day-after-day, and lot-after-lot.
Sensitivity – detect even the lowest sample concentration
Broad Range – minimize need for dilution
Consistent – strict quality control guidelines ensure reproducible results, lot-after-lot
Trusted – reliability highlighted in peer-reviewed publications for three decades
Highly specific antibodies validated for various applications, from flow cytometry to IHC, to help you discover immune checkpoint inhibitors, develop novel
immunotherapies, and support your immuno-oncology research.